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SourcesNames Used
PharmacoGx ciclosporin

External IDs

Smiles: CCC1C(=O)N(CC(=O)N(C(C(=O)NC(C(=O)N(C(C(=O)NC(C(=O)NC(C(=O)N(C(C(=O)N(C(C(=O)N(C(C(=O)N(C(C(=O)N1)C(C(C)CC=CC)O)C)C(C)C)C)CC(C)C)C)CC(C)C)C)C)C)CC(C)C)C)C(C)C)CC(C)C)C)C
Pubchem: 6435893

Annotated Targets


Cell lines tested with ciclosporin

808 cell lines have been tested with this compound, using data from 1 dataset(s).
A549 lung CTRPv23
DU-145 prostate CTRPv22
AsPC-1 pancreas CTRPv22
NCI-H1869 lung CTRPv22
CCF-STTG1 central nervous system CTRPv22
OAW-28 ovary CTRPv22
HeLa cervix CTRPv22
LOXIMVI haematopoietic and lymphoid tissue CTRPv22
NCI-H520 lung CTRPv22
MKN74 stomach CTRPv22
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Top molecular features associated with response to ciclosporin

Feature TypeStandardized
Nominal ANOVA
mRNA TNFRSF17 CTRPv2 AAC 0.18 2e-06
mRNA COL5A3 CTRPv2 AAC 0.18 2e-06
mRNA LIME1 CTRPv2 AAC 0.18 2e-06
mRNA VPS4B CTRPv2 AAC 0.17 2e-06
mRNA TXNDC5 CTRPv2 AAC 0.18 3e-06
mRNA MBD1 CTRPv2 AAC 0.19 3e-06
mRNA AL591806.1 CTRPv2 AAC 0.19 3e-06
mRNA MYL7 CTRPv2 AAC 0.17 4e-06
mRNA KRTAP11-1 CTRPv2 AAC 0.17 4e-06
mRNA DLGAP1 CTRPv2 AAC 0.17 4e-06
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