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SourcesNames Used
PharmacoGx ciclosporin

External IDs

Smiles: CCC1C(=O)N(CC(=O)N(C(C(=O)NC(C(=O)N(C(C(=O)NC(C(=O)NC(C(=O)N(C(C(=O)N(C(C(=O)N(C(C(=O)N(C(C(=O)N1)C(C(C)CC=CC)O)C)C(C)C)C)CC(C)C)C)CC(C)C)C)C)C)CC(C)C)C)C(C)C)CC(C)C)C)C
Pubchem: 6435893

Annotated Targets


Cell lines tested with ciclosporin

808 cell lines have been tested with this compound, using data from 1 dataset(s).
A549 lung CTRPv23
DU-145 prostate CTRPv22
AsPC-1 pancreas CTRPv22
NCI-H1869 lung CTRPv22
CCF-STTG1 central nervous system CTRPv22
OAW-28 ovary CTRPv22
HeLa cervix CTRPv22
LOXIMVI haematopoietic and lymphoid tissue CTRPv22
NCI-H520 lung CTRPv22
MKN74 stomach CTRPv22
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Top molecular features associated with response to ciclosporin

Feature TypeStandardized
Nominal ANOVA
mRNA JCHAIN CTRPv2 AAC 0.24 4e-10
mRNA ENAM CTRPv2 AAC 0.23 3e-09
mRNA MZB1 CTRPv2 AAC 0.23 9e-08
mRNA FKBP11 CTRPv2 AAC 0.2 1e-07
mRNA PIGN CTRPv2 AAC 0.2 2e-07
mRNA INPP4A CTRPv2 AAC 0.2 2e-07
mRNA BTN1A1 CTRPv2 AAC 0.18 4e-07
mRNA LMAN1 CTRPv2 AAC 0.2 4e-07
mRNA RP4-583P15.14 CTRPv2 AAC 0.19 6e-07
mRNA CXXC1 CTRPv2 AAC 0.22 6e-07
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