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AEW541

Synonyms

SourcesNames Used
CCLEAEW541
PharmacoGx AEW541

External IDs

DatabaseIdentifier
Smiles: C1CN(C1)CC2CC(C2)N3C=C(C4=C3N=CN=C4N)C5=CC(=CC=C5)OCC6=CC=CC=C6
Inchikey: AECDBHGVIIRMOI-UHFFFAOYSA-N
Pubchem: 11476171

Annotated Targets

IGF1R

Cell lines tested with AEW541

503 cell lines have been tested with this compound, using data from 1 dataset(s).
ZR-75-30 breast CCLE1
ZR-75-1 breast CCLE1
YKG-1 central nervous system CCLE1
WM-983B skin CCLE1
WM-88 skin CCLE1
WM-793 skin CCLE1
WM-266-4 skin CCLE1
WM1799 skin CCLE1
WM-115 skin CCLE1
VMRC-RCZ kidney CCLE1
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Top molecular features associated with response to AEW541


Feature TypeStandardized
Nominal ANOVA
mRNA EML6 CCLE AAC -0.00015 1
mRNA UPK1A CCLE AAC -0.00014 1
mRNA ZNF568 CCLE AAC 0.00012 1
mRNA LRRC4B CCLE AAC -0.00012 1
mRNA GDPD5 CCLE AAC 0.00012 1
mRNA BRIX1 CCLE AAC -0.00011 1
mRNA PCSK1 CCLE AAC -0.0001 1
mRNA GRN CCLE AAC -9.8e-05 1
mRNA GNA14 CCLE AAC -7.3e-05 1
mRNA ZNF26 CCLE AAC -6.9e-05 1
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