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AEW541

Synonyms

SourcesNames Used
CCLEAEW541
PharmacoGx AEW541

External IDs

DatabaseIdentifier
Smiles: C1CN(C1)CC2CC(C2)N3C=C(C4=C3N=CN=C4N)C5=CC(=CC=C5)OCC6=CC=CC=C6
Inchikey: AECDBHGVIIRMOI-UHFFFAOYSA-N
Pubchem: 11476171

Annotated Targets

IGF1R

Cell lines tested with AEW541

503 cell lines have been tested with this compound, using data from 1 dataset(s).
ZR-75-30 breast CCLE1
ZR-75-1 breast CCLE1
YKG-1 central nervous system CCLE1
WM-983B skin CCLE1
WM-88 skin CCLE1
WM-793 skin CCLE1
WM-266-4 skin CCLE1
WM1799 skin CCLE1
WM-115 skin CCLE1
VMRC-RCZ kidney CCLE1
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Top molecular features associated with response to AEW541


Feature TypeStandardized
Nominal ANOVA
mRNA PTPRC CCLE AAC -0.42 2e-08
mRNA NLRC3 CCLE AAC -0.42 6e-09
mRNA SASH3 CCLE AAC -0.4 2e-08
mRNA NCKAP1L CCLE AAC -0.39 4e-07
mRNA MYO1G CCLE AAC -0.35 1e-06
mRNA KLHL6 CCLE AAC -0.33 6e-05
mRNA TBC1D10C CCLE AAC -0.32 3e-06
mRNA DENND1C CCLE AAC -0.32 2e-06
mRNA GPR65 CCLE AAC -0.31 1e-07
mRNA STAP1 CCLE AAC -0.31 5e-07
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