1. Home/
  2. Compounds/
  3. AEW541

AEW541

Synonyms

SourcesNames Used
CCLEAEW541
PharmacoGx AEW541

External IDs

DatabaseIdentifier
Smiles: C1CN(C1)CC2CC(C2)N3C=C(C4=C3N=CN=C4N)C5=CC(=CC=C5)OCC6=CC=CC=C6
Inchikey: AECDBHGVIIRMOI-UHFFFAOYSA-N
Pubchem: 11476171

Annotated Targets

IGF1R

Cell lines tested with AEW541

503 cell lines have been tested with this compound, using data from 1 dataset(s).
A204 soft tissue CCLE1
A172 central nervous system CCLE1
8-MG-BA central nervous system CCLE1
8505C thyroid CCLE1
8305C thyroid CCLE1
786-0 kidney CCLE1
769-P kidney CCLE1
697 haematopoietic and lymphoid tissue CCLE1
639-V urinary tract CCLE1
5637 urinary tract CCLE1
Download CSV
Download Data as CSV

Top molecular features associated with response to AEW541


Feature TypeStandardized
Nominal ANOVA
mRNA AMPD1 CCLE AAC 0.31 1e-11
mRNA IGF1R CCLE AAC 0.32 1e-11
mRNA TP53INP1 CCLE AAC 0.29 7e-10
mRNA GPRC5D CCLE AAC 0.28 7e-10
mRNA DEK CCLE AAC -0.27 1e-09
mRNA NLRC3 CCLE AAC -0.42 6e-09
mRNA PTPRC CCLE AAC -0.42 2e-08
mRNA SASH3 CCLE AAC -0.4 2e-08
mRNA SWT1 CCLE AAC 0.26 2e-08
mRNA C1orf56 CCLE AAC 0.26 3e-08
Download CSV