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cediranib

Synonyms

SourcesNames Used
CTRPv2cediranib
PharmacoGx cediranib

External IDs

DatabaseIdentifier
Smiles: COc1cc2c(Oc3ccc4[nH]c(C)cc4c3F)ncnc2cc1OCCCN1CCCC1
Pubchem: 9933475

Annotated Targets

KIT, CSF1R, FLT1, FLT3, FLT4, KDR, PDGFRA, PDGFRB

Cell lines tested with cediranib

439 cell lines have been tested with this compound, using data from 1 dataset(s).
DU-145 prostate CTRPv22
AsPC-1 pancreas CTRPv22
NCI-H1869 lung CTRPv22
CCF-STTG1 central nervous system CTRPv22
YAMATO N/A CTRPv21
TTC709 N/A CTRPv21
TM87-16 N/A CTRPv21
SYO1 N/A CTRPv21
SW982 soft tissue CTRPv21
BT16 N/A CTRPv21
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Top molecular features associated with response to cediranib


Feature TypeStandardized
Nominal ANOVA
mRNA GOLGA8M CTRPv2 AAC 0.38 1e-14
mRNA PRSS57 CTRPv2 AAC 0.39 2e-14
mRNA GOLGA8J CTRPv2 AAC 0.37 1e-13
mRNA TIFAB CTRPv2 AAC 0.34 1e-11
mRNA PDGFRA CTRPv2 AAC 0.35 2e-11
mRNA RP11-231C18.3 CTRPv2 AAC 0.35 2e-11
mRNA DCANP1 CTRPv2 AAC 0.34 2e-11
mRNA GOLGA8T CTRPv2 AAC 0.33 1e-10
mRNA FRY CTRPv2 AAC 0.32 3e-10
mRNA SNAI3 CTRPv2 AAC 0.35 5e-10
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