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canertinib

Synonyms

SourcesNames Used
CTRPv2canertinib
PharmacoGx canertinib

External IDs

DatabaseIdentifier
Smiles: Fc1ccc(Nc2ncnc3cc(OCCCN4CCOCC4)c(NC(=O)C=C)cc23)cc1Cl
Pubchem: 156414

Annotated Targets

ERBB4, EGFR, ERBB2, AKT1

Cell lines tested with canertinib

799 cell lines have been tested with this compound, using data from 1 dataset(s).
A549 lung CTRPv23
DU-145 prostate CTRPv22
AsPC-1 pancreas CTRPv22
NCI-H1869 lung CTRPv22
CCF-STTG1 central nervous system CTRPv22
OAW-28 ovary CTRPv22
HeLa cervix CTRPv22
LOXIMVI haematopoietic and lymphoid tissue CTRPv22
NCI-H520 lung CTRPv22
MKN74 stomach CTRPv22
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Top molecular features associated with response to canertinib


Feature TypeStandardized
Nominal ANOVA
mRNA PKP3 CTRPv2 AAC 0.34 2e-12
mRNA CLDN4 CTRPv2 AAC 0.29 4e-12
mRNA ERBB2 CTRPv2 AAC 0.26 8e-12
mRNA LAD1 CTRPv2 AAC 0.3 1e-11
mRNA CDC42BPG CTRPv2 AAC 0.29 8e-11
mRNA MUC22 CTRPv2 AAC 0.22 1e-10
mRNA STX2 CTRPv2 AAC -0.26 2e-10
mRNA EGFR CTRPv2 AAC 0.24 3e-10
mRNA SPINT1 CTRPv2 AAC 0.27 5e-10
mRNA GRHL1 CTRPv2 AAC 0.25 6e-10
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