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BX-912

Synonyms

SourcesNames Used
GDSC1000BX-912
PharmacoGx BX-912

External IDs

DatabaseIdentifier
Smiles: Brc1cnc(Nc2cccc(NC(=O)N3CCCC3)c2)nc1NCCc4c[nH]cn4
Pubchem: 11754511

Annotated Targets

CDK2, CHEK1, GSK3B, KDR, PDK1, PDPK1

Cell lines tested with BX-912

984 cell lines have been tested with this compound, using data from 1 dataset(s).
NB14 autonomic ganglia GDSC10001
MDA-MB-453 breast GDSC10001
BOKU cervix GDSC10001
HuCCT1 biliary tract GDSC10001
ES4 bone GDSC10001
HSC-3 upper aerodigestive tract GDSC10001
PCI-30 head and neck GDSC10001
UACC-257 haematopoietic and lymphoid tissue GDSC10001
SK-MEL-28 haematopoietic and lymphoid tissue GDSC10001
KS-1 central nervous system GDSC10001
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Top molecular features associated with response to BX-912


Feature TypeStandardized
Nominal ANOVA
mRNA ALOX12 GDSC1000 AAC -3.7e-05 1
mRNA POU3F4 GDSC1000 AAC 3.4e-05 1
mRNA PRICKLE4 GDSC1000 AAC 2.9e-05 1
mRNA CACNA1F GDSC1000 AAC 2.1e-05 1
mRNA TRHR GDSC1000 AAC 1.5e-05 1
mRNA PFDN2 GDSC1000 AAC 1.2e-05 1
mRNA ANGEL1 GDSC1000 AAC -1.2e-05 1
mRNA CAPN15 GDSC1000 AAC -7.1e-06 1
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