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BX-912

Synonyms

SourcesNames Used
GDSC1000BX-912
PharmacoGx BX-912

External IDs

DatabaseIdentifier
Smiles: Brc1cnc(Nc2cccc(NC(=O)N3CCCC3)c2)nc1NCCc4c[nH]cn4
Pubchem: 11754511

Annotated Targets

CDK2, CHEK1, GSK3B, KDR, PDK1, PDPK1

Cell lines tested with BX-912

984 cell lines have been tested with this compound, using data from 1 dataset(s).
NB14 autonomic ganglia GDSC10001
MDA-MB-453 breast GDSC10001
BOKU cervix GDSC10001
HuCCT1 biliary tract GDSC10001
ES4 bone GDSC10001
HSC-3 upper aerodigestive tract GDSC10001
PCI-30 head and neck GDSC10001
UACC-257 haematopoietic and lymphoid tissue GDSC10001
SK-MEL-28 haematopoietic and lymphoid tissue GDSC10001
KS-1 central nervous system GDSC10001
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Top molecular features associated with response to BX-912


Feature TypeStandardized
Nominal ANOVA
mRNA NCKAP1 GDSC1000 AAC -0.32 9e-09
mRNA SDC4 GDSC1000 AAC -0.3 1e-12
mRNA MGAT4B GDSC1000 AAC -0.29 6e-17
mRNA LGALS3 GDSC1000 AAC -0.29 5e-17
mRNA LMNA GDSC1000 AAC -0.29 7e-14
mRNA TNFRSF12A GDSC1000 AAC -0.28 3e-11
mRNA SQSTM1 GDSC1000 AAC -0.28 2e-17
mRNA TMBIM1 GDSC1000 AAC -0.28 8e-16
mRNA TJP1 GDSC1000 AAC -0.28 8e-07
mRNA CAST GDSC1000 AAC -0.28 2e-16
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