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BX-795

Synonyms

SourcesNames Used
GDSC1000BX-795
PharmacoGx BX-795

External IDs

DatabaseIdentifier
Smiles: C1CCN(C1)C(=O)NC2=CC=CC(=C2)NC3=NC=C(C(=N3)NCCCNC(=O)C4=CC=CS4)I
Inchikey: VAVXGGRQQJZYBL-UHFFFAOYSA-N
Pubchem: 10077147

Annotated Targets

CDK2, CHEK1, GSK3B, KDR, PDK1, PDPK1

Cell lines tested with BX-795

889 cell lines have been tested with this compound, using data from 1 dataset(s).
LNZTA3WT4 central nervous system GDSC10001
U-87-MG central nervous system GDSC10001
HuO9 bone GDSC10001
CCF-STTG1 central nervous system GDSC10001
COLO-824 breast GDSC10001
OVCAR-8 ovary GDSC10001
WSU-NHL haematopoietic and lymphoid tissue GDSC10001
MEG-01 haematopoietic and lymphoid tissue GDSC10001
NCI-H2009 lung GDSC10001
SNU-C2B large intestine GDSC10001
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Top molecular features associated with response to BX-795


Feature TypeStandardized
Nominal ANOVA
mRNA CD300LF GDSC1000 AAC 0.24 1e-11
mRNA MYO1F GDSC1000 AAC 0.26 2e-11
mRNA MRC2 GDSC1000 AAC 0.27 6e-11
mRNA CD80 GDSC1000 AAC -0.24 8e-11
mRNA MS4A6A GDSC1000 AAC 0.22 1e-10
mRNA KCNE5 GDSC1000 AAC 0.21 1e-10
mRNA ADGRA2 GDSC1000 AAC 0.25 2e-10
mRNA ATP8B4 GDSC1000 AAC 0.22 3e-10
mRNA RFX8 GDSC1000 AAC 0.22 6e-10
mRNA OCSTAMP GDSC1000 AAC 0.21 7e-10
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