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BX-795

Synonyms

SourcesNames Used
GDSC1000BX-795
PharmacoGx BX-795

External IDs

DatabaseIdentifier
Smiles: C1CCN(C1)C(=O)NC2=CC=CC(=C2)NC3=NC=C(C(=N3)NCCCNC(=O)C4=CC=CS4)I
Inchikey: VAVXGGRQQJZYBL-UHFFFAOYSA-N
Pubchem: 10077147

Annotated Targets

CDK2, CHEK1, GSK3B, KDR, PDK1, PDPK1

Cell lines tested with BX-795

889 cell lines have been tested with this compound, using data from 1 dataset(s).
LNZTA3WT4 central nervous system GDSC10001
U-87-MG central nervous system GDSC10001
HuO9 bone GDSC10001
CCF-STTG1 central nervous system GDSC10001
COLO-824 breast GDSC10001
OVCAR-8 ovary GDSC10001
WSU-NHL haematopoietic and lymphoid tissue GDSC10001
MEG-01 haematopoietic and lymphoid tissue GDSC10001
NCI-H2009 lung GDSC10001
SNU-C2B large intestine GDSC10001
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Top molecular features associated with response to BX-795


Feature TypeStandardized
Nominal ANOVA
mRNA NCKAP1 GDSC1000 AAC -0.28 5e-05
mRNA CD80 GDSC1000 AAC -0.24 8e-11
mRNA CD48 GDSC1000 AAC -0.24 4e-06
mRNA WASL GDSC1000 AAC -0.23 1e-05
mRNA MANBAL GDSC1000 AAC -0.23 1e-05
mRNA RASGRP3 GDSC1000 AAC -0.23 4e-09
mRNA SGCE GDSC1000 AAC -0.22 7e-08
mRNA MREG GDSC1000 AAC -0.21 4e-09
mRNA ANGPTL6 GDSC1000 AAC -0.21 1e-07
mRNA MS4A1 GDSC1000 AAC -0.21 1e-07
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