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BX-795

Synonyms

SourcesNames Used
GDSC1000BX-795
PharmacoGx BX-795

External IDs

DatabaseIdentifier
Smiles: C1CCN(C1)C(=O)NC2=CC=CC(=C2)NC3=NC=C(C(=N3)NCCCNC(=O)C4=CC=CS4)I
Inchikey: VAVXGGRQQJZYBL-UHFFFAOYSA-N
Pubchem: 10077147

Annotated Targets

CDK2, CHEK1, GSK3B, KDR, PDK1, PDPK1

Cell lines tested with BX-795

889 cell lines have been tested with this compound, using data from 1 dataset(s).
201T lung GDSC10001
22RV1 prostate GDSC10001
23132-87 stomach GDSC10001
42-MG-BA central nervous system GDSC10001
451Lu skin GDSC10001
5637 urinary tract GDSC10001
639-V urinary tract GDSC10001
647-V urinary tract GDSC10001
697 haematopoietic and lymphoid tissue GDSC10001
786-0 kidney GDSC10001
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Top molecular features associated with response to BX-795


Feature TypeStandardized
Nominal ANOVA
mRNA PRSS57 GDSC1000 AAC 0.28 2e-15
mRNA CACNA2D4 GDSC1000 AAC 0.27 2e-14
mRNA B3GNTL1 GDSC1000 AAC 0.26 3e-14
mRNA PPP1R27 GDSC1000 AAC 0.24 2e-13
mRNA FLT3 GDSC1000 AAC 0.26 2e-13
mRNA GNA15 GDSC1000 AAC 0.28 4e-13
mRNA TIFAB GDSC1000 AAC 0.23 1e-12
mRNA LAIR1 GDSC1000 AAC 0.31 1e-12
mRNA CTSG GDSC1000 AAC 0.25 3e-12
mRNA SIGLEC7 GDSC1000 AAC 0.23 1e-11
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