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BX-795

Synonyms

SourcesNames Used
GDSC1000BX-795
PharmacoGx BX-795

External IDs

DatabaseIdentifier
Smiles: C1CCN(C1)C(=O)NC2=CC=CC(=C2)NC3=NC=C(C(=N3)NCCCNC(=O)C4=CC=CS4)I
Inchikey: VAVXGGRQQJZYBL-UHFFFAOYSA-N
Pubchem: 10077147

Annotated Targets

CDK2, CHEK1, GSK3B, KDR, PDK1, PDPK1

Cell lines tested with BX-795

889 cell lines have been tested with this compound, using data from 1 dataset(s).
SK-ES-1 bone GDSC10001
CW-2 large intestine GDSC10001
KELLY autonomic ganglia GDSC10001
SKM-1 haematopoietic and lymphoid tissue GDSC10001
CCRF-CEM haematopoietic and lymphoid tissue GDSC10001
NCI-H2452 pleura GDSC10001
SK-N-FI autonomic ganglia GDSC10001
K1 thyroid GDSC10001
SiHa cervix GDSC10001
SK-N-AS autonomic ganglia GDSC10001
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Top molecular features associated with response to BX-795


Feature TypeStandardized
Nominal ANOVA
mRNA PRSS57 GDSC1000 AAC 0.28 2e-15
mRNA CACNA2D4 GDSC1000 AAC 0.27 2e-14
mRNA B3GNTL1 GDSC1000 AAC 0.26 3e-14
mRNA PPP1R27 GDSC1000 AAC 0.24 2e-13
mRNA FLT3 GDSC1000 AAC 0.26 2e-13
mRNA GNA15 GDSC1000 AAC 0.28 4e-13
mRNA TIFAB GDSC1000 AAC 0.23 1e-12
mRNA LAIR1 GDSC1000 AAC 0.31 1e-12
mRNA CTSG GDSC1000 AAC 0.25 3e-12
mRNA SIGLEC7 GDSC1000 AAC 0.23 1e-11
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