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BX-795

Synonyms

SourcesNames Used
GDSC1000BX-795
PharmacoGx BX-795

External IDs

DatabaseIdentifier
Smiles: C1CCN(C1)C(=O)NC2=CC=CC(=C2)NC3=NC=C(C(=N3)NCCCNC(=O)C4=CC=CS4)I
Inchikey: VAVXGGRQQJZYBL-UHFFFAOYSA-N
Pubchem: 10077147

Annotated Targets

CDK2, CHEK1, GSK3B, KDR, PDK1, PDPK1

Cell lines tested with BX-795

889 cell lines have been tested with this compound, using data from 1 dataset(s).
LNZTA3WT4 central nervous system GDSC10001
U-87-MG central nervous system GDSC10001
HuO9 bone GDSC10001
CCF-STTG1 central nervous system GDSC10001
COLO-824 breast GDSC10001
OVCAR-8 ovary GDSC10001
WSU-NHL haematopoietic and lymphoid tissue GDSC10001
MEG-01 haematopoietic and lymphoid tissue GDSC10001
NCI-H2009 lung GDSC10001
SNU-C2B large intestine GDSC10001
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Top molecular features associated with response to BX-795


Feature TypeStandardized
Nominal ANOVA
mRNA PRSS57 GDSC1000 AAC 0.28 2e-15
mRNA CACNA2D4 GDSC1000 AAC 0.27 2e-14
mRNA B3GNTL1 GDSC1000 AAC 0.26 3e-14
mRNA PPP1R27 GDSC1000 AAC 0.24 2e-13
mRNA FLT3 GDSC1000 AAC 0.26 2e-13
mRNA GNA15 GDSC1000 AAC 0.28 4e-13
mRNA TIFAB GDSC1000 AAC 0.23 1e-12
mRNA LAIR1 GDSC1000 AAC 0.31 1e-12
mRNA CTSG GDSC1000 AAC 0.25 3e-12
mRNA SIGLEC7 GDSC1000 AAC 0.23 1e-11
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