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Bryostatin 1

Synonyms

SourcesNames Used
GDSC1000, FIMMBryostatin 1
PharmacoGx Bryostatin 1

External IDs

DatabaseIdentifier
Smiles: CCCC=CC=CC(=O)OC1C(=CC(=O)OC)CC2CC(OC(=O)CC(CC3CC(C(C(O3)(CC4CC(=CC(=O)OC)CC(O4)C=CC(C1(O2)O)(C)C)O)(C)C)OC(=O)C)O)C(C)O
Inchikey: MJQUEDHRCUIRLF-KOWVOJLTSA-N
Pubchem: 5477635

Cell lines tested with Bryostatin 1

940 cell lines have been tested with this compound, using data from 2 dataset(s).
CAL-120 breast GDSC1000, FIMM2
HCC1143 breast GDSC1000, FIMM2
CAL-85-1 breast GDSC1000, FIMM2
T47D breast GDSC1000, FIMM2
OVCAR-5 ovary GDSC1000, FIMM2
ML-2 haematopoietic and lymphoid tissue GDSC1000, FIMM2
OVCAR-8 ovary GDSC1000, FIMM2
THP-1 haematopoietic and lymphoid tissue GDSC1000, FIMM2
MDA-MB-453 breast GDSC1000, FIMM2
MV-4-11 haematopoietic and lymphoid tissue GDSC1000, FIMM2
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Top molecular features associated with response to Bryostatin 1


Feature TypeStandardized
Nominal ANOVA
mRNA ITGB5 GDSC1000 AAC 0.25 1e-08
mRNA FOS GDSC1000 AAC 0.24 1e-08
mRNA TCF4 GDSC1000 AAC -0.24 3e-08
mRNA IER5L GDSC1000 AAC 0.22 7e-08
mRNA AVPI1 GDSC1000 AAC 0.22 3e-07
mRNA DUSP1 GDSC1000 AAC 0.2 3e-07
mRNA EGR1 GDSC1000 AAC 0.2 4e-07
mRNA NR1H2 GDSC1000 AAC 0.18 6e-07
mRNA SLC16A4 GDSC1000 AAC 0.19 6e-07
mRNA MAFK GDSC1000 AAC 0.18 8e-07
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