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brivanib

Synonyms

SourcesNames Used
CTRPv2brivanib
PharmacoGx brivanib

External IDs

DatabaseIdentifier
Smiles: C[C@@H](O)COc1cn2ncnc(Oc3ccc4[nH]c(C)cc4c3F)c2c1C
Pubchem: 11234052

Annotated Targets

CYP3A4, FGFR1, FLT1, KCNH2, KDR

Cell lines tested with brivanib

810 cell lines have been tested with this compound, using data from 1 dataset(s).
A549 lung CTRPv23
DU-145 prostate CTRPv22
AsPC-1 pancreas CTRPv22
NCI-H1869 lung CTRPv22
CCF-STTG1 central nervous system CTRPv22
OAW-28 ovary CTRPv22
HeLa cervix CTRPv22
LOXIMVI haematopoietic and lymphoid tissue CTRPv22
NCI-H520 lung CTRPv22
MKN74 stomach CTRPv22
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Top molecular features associated with response to brivanib


Feature TypeStandardized
Nominal ANOVA
mRNA LMNB1 CTRPv2 AAC 0.23 5e-09
mRNA GK CTRPv2 AAC 0.2 2e-08
mRNA NANP CTRPv2 AAC 0.2 3e-08
mRNA USP7 CTRPv2 AAC 0.2 5e-08
mRNA WNT8B CTRPv2 AAC 0.19 6e-08
mRNA NDUFB9 CTRPv2 AAC 0.19 6e-08
mRNA F5 CTRPv2 AAC 0.19 1e-07
mRNA ARHGAP19-SLIT1 CTRPv2 AAC 0.22 2e-07
mRNA OLFM3 CTRPv2 AAC 0.18 2e-07
mRNA RP11-411B6.6 CTRPv2 AAC 0.19 2e-07
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