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ABT-737

Synonyms

SourcesNames Used
CTRPv2ABT-737
PharmacoGx ABT-737

External IDs

DatabaseIdentifier
Smiles: CN(C)CCC(CSC1=CC=CC=C1)NC2=C(C=C(C=C2)S(=O)(=O)NC(=O)C3=CC=C(C=C3)N4CCN(CC4)CC5=CC=CC=C5C6=CC=C(C=C6)Cl)[N+](=O)[O-]
Inchikey: HPLNQCPCUACXLM-PGUFJCEWSA-N
Pubchem: 11228183

Annotated Targets

BCL2, BCL2L1, BCL2L2

Cell lines tested with ABT-737

773 cell lines have been tested with this compound, using data from 1 dataset(s).
CAS-1 central nervous system CTRPv21
KPL-1 breast CTRPv21
MKN1 stomach CTRPv21
253J-BV urinary tract CTRPv21
BFTC-905 urinary tract CTRPv21
BFTC-909 urinary tract CTRPv21
CAL-120 breast CTRPv21
CAL-29 urinary tract CTRPv21
CAL-62 thyroid CTRPv21
HuCCT1 biliary tract CTRPv21
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Top molecular features associated with response to ABT-737


Feature TypeStandardized
Nominal ANOVA
mRNA NEURL1B CTRPv2 AAC 0.32 3e-18
mRNA ARHGAP33 CTRPv2 AAC 0.32 3e-17
mRNA BCL2 CTRPv2 AAC 0.32 6e-16
mRNA ACTL6B CTRPv2 AAC 0.3 2e-15
mRNA KIAA1147 CTRPv2 AAC 0.28 2e-14
mRNA FIZ1 CTRPv2 AAC 0.28 2e-14
mRNA CELF4 CTRPv2 AAC 0.28 3e-14
mRNA ZNF737 CTRPv2 AAC 0.28 5e-14
mRNA ZNF606 CTRPv2 AAC 0.28 7e-14
mRNA VPS4B CTRPv2 AAC 0.26 8e-14
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