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ABT-737

Synonyms

SourcesNames Used
CTRPv2ABT-737
PharmacoGx ABT-737

External IDs

DatabaseIdentifier
Smiles: CN(C)CCC(CSC1=CC=CC=C1)NC2=C(C=C(C=C2)S(=O)(=O)NC(=O)C3=CC=C(C=C3)N4CCN(CC4)CC5=CC=CC=C5C6=CC=C(C=C6)Cl)[N+](=O)[O-]
Inchikey: HPLNQCPCUACXLM-PGUFJCEWSA-N
Pubchem: 11228183

Annotated Targets

BCL2, BCL2L1, BCL2L2

FDA Approval Status

Not Approved
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Top molecular features associated with response to ABT-737


Feature TypeStandardized
Nominal ANOVA
mRNA GDSC1000 pan-cancer AAC 0.18 6e-05
mRNA gCSI pan-cancer AAC -0.22 9e-05
mRNA GDSC1000 pan-cancer AAC 0.12 0.0001
mRNA CCLE pan-cancer AAC 0.17 0.0002
mRNA GDSC1000 pan-cancer AAC 0.11 0.0003
mRNA CTRPv2 pan-cancer AAC -0.12 0.0004
mRNA GDSC1000 pan-cancer AAC 0.11 0.0007
mRNA GDSC1000 pan-cancer AAC -0.11 0.0007
mRNA CTRPv2 pan-cancer AAC -0.11 0.0007
mRNA GDSC1000 pan-cancer AAC 0.12 0.0008
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