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ABT-263

Synonyms

SourcesNames Used
GDSC1000, FIMMNavitoclax
CTRPv2navitoclax
PharmacoGx ABT-263

External IDs

DatabaseIdentifier
Smiles: CC1(CCC(=C(C1)CN2CCN(CC2)C3=CC=C(C=C3)C(=O)NS(=O)(=O)C4=CC(=C(C=C4)NC(CCN5CCOCC5)CSC6=CC=CC=C6)S(=O)(=O)C(F)(F)F)C7=CC=C(C=C7)Cl)C
Inchikey: JLYAXFNOILIKPP-KXQOOQHDSA-N
Pubchem: 24978538

Annotated Targets

BCL2, BCL2L2, BAD

FDA Approval Status

Not Approved
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Top molecular features associated with response to ABT-263


Feature TypeStandardized
Nominal ANOVA
mRNA CTRPv2 pan-cancer AAC 0.26 0.0002
mRNA GDSC1000 pan-cancer AAC -0.12 0.0002
mRNA GDSC1000 pan-cancer AAC -0.1 0.0003
mRNA GDSC1000 pan-cancer AAC -0.11 0.001
mRNA CTRPv2 pan-cancer AAC 0.12 0.001
mRNA CCLE pan-cancer AAC 0.14 0.002
mRNA GDSC1000 pan-cancer AAC -0.1 0.002
mRNA GDSC1000 pan-cancer AAC -0.1 0.003
mRNA GDSC1000 pan-cancer AAC -0.079 0.004
mRNA GDSC1000 pan-cancer AAC -0.1 0.004
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