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SourcesNames Used
PharmacoGx A-770041

External IDs

Smiles: CC(=O)N1CCN(CC1)C2CCC(CC2)N3C4=C(C(=N3)C5=CC(=C(C=C5)NC(=O)C6=CC7=CC=CC=C7N6C)OC)C(=NC=N4)N
Pubchem: 9549184

Cell lines tested with A-770041

427 cell lines have been tested with this compound, using data from 1 dataset(s).
RPMI-8226 haematopoietic and lymphoid tissue GDSC10001
NB5 autonomic ganglia GDSC10001
MKL-1-subclone-2 skin GDSC10001
JiyoyeP-2003 haematopoietic and lymphoid tissue GDSC10001
MY-M12 haematopoietic and lymphoid tissue GDSC10001
NB1 autonomic ganglia GDSC10001
ROS-50 haematopoietic and lymphoid tissue GDSC10001
NCI-H524 lung GDSC10001
CHP-126 autonomic ganglia GDSC10001
NEC8 testis GDSC10001
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Top molecular features associated with response to A-770041

Feature TypeStandardized
Nominal ANOVA
mRNA FCRL1 GDSC1000 AAC 0.34 3e-11
mRNA CD19 GDSC1000 AAC 0.35 3e-10
mRNA USP6NL GDSC1000 AAC 0.33 4e-10
mRNA C17orf99 GDSC1000 AAC 0.31 6e-10
mRNA FCRL2 GDSC1000 AAC 0.31 7e-10
mRNA PCED1B GDSC1000 AAC 0.32 2e-09
mRNA CD79B GDSC1000 AAC 0.34 3e-09
mRNA GRAP GDSC1000 AAC 0.36 4e-09
mRNA CD22 GDSC1000 AAC 0.31 1e-08
mRNA TIAM2 GDSC1000 AAC 0.28 2e-08
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