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A-443654

Synonyms

SourcesNames Used
GDSC1000A-443654
PharmacoGx A-443654

External IDs

DatabaseIdentifier
Smiles: CC1=C2C=C(C=CC2=NN1)C3=CC(=CN=C3)OCC(CC4=CNC5=CC=CC=C54)N
Inchikey: YWTBGJGMTBHQTM-IBGZPJMESA-N
Pubchem: 10172943

Cell lines tested with A-443654

426 cell lines have been tested with this compound, using data from 1 dataset(s).
no-11 central nervous system GDSC10001
no-10 central nervous system GDSC10001
YT haematopoietic and lymphoid tissue GDSC10001
WSU-NHL haematopoietic and lymphoid tissue GDSC10001
WSU-DLCL2 haematopoietic and lymphoid tissue GDSC10001
WIL2-NS haematopoietic and lymphoid tissue GDSC10001
VCaP prostate GDSC10001
VA-ES-BJ bone GDSC10001
UACC-257 haematopoietic and lymphoid tissue GDSC10001
U-87-MG central nervous system GDSC10001
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Top molecular features associated with response to A-443654


Feature TypeStandardized
Nominal ANOVA
mRNA HNRNPK GDSC1000 AAC 0.2 0.0002
mRNA ARF6 GDSC1000 AAC 0.21 0.0002
mRNA TMEM55A GDSC1000 AAC -0.21 0.0003
mRNA C1GALT1C1 GDSC1000 AAC 0.2 0.0003
mRNA ASIP GDSC1000 AAC -0.19 0.0003
mRNA PPP1R2 GDSC1000 AAC 0.19 0.0004
mRNA ANO10 GDSC1000 AAC -0.19 0.0004
mRNA SPG21 GDSC1000 AAC -0.18 0.0004
mRNA HFE GDSC1000 AAC 0.21 0.0005
mRNA C1orf216 GDSC1000 AAC -0.18 0.0005
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