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SourcesNames Used
PharmacoGx A-443654

External IDs

Smiles: CC1=C2C=C(C=CC2=NN1)C3=CC(=CN=C3)OCC(CC4=CNC5=CC=CC=C54)N
Pubchem: 10172943

Cell lines tested with A-443654

426 cell lines have been tested with this compound, using data from 1 dataset(s).
ES4 bone GDSC10001
HUTU-80 small intestine GDSC10001
ES8 bone GDSC10001
JAR testis GDSC10001
MHH-PREB-1 haematopoietic and lymphoid tissue GDSC10001
NCI-H1304 lung GDSC10001
AMO-1 haematopoietic and lymphoid tissue GDSC10001
NCI-H747 large intestine GDSC10001
NCI-H748 lung GDSC10001
KMOE-2 haematopoietic and lymphoid tissue GDSC10001
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Top molecular features associated with response to A-443654

Feature TypeStandardized
Nominal ANOVA
mRNA ABCB1 GDSC1000 AAC -0.28 1e-06
mRNA PRRT4 GDSC1000 AAC -0.26 2e-05
mRNA SEC62 GDSC1000 AAC 0.21 2e-05
mRNA SLURP1 GDSC1000 AAC 0.22 3e-05
mRNA CD38 GDSC1000 AAC 0.28 4e-05
mRNA OLFML2A GDSC1000 AAC 0.27 4e-05
mRNA LY9 GDSC1000 AAC 0.23 5e-05
mRNA HAP1 GDSC1000 AAC -0.21 9e-05
mRNA TMEM229A GDSC1000 AAC -0.25 0.0001
mRNA TBKBP1 GDSC1000 AAC -0.21 0.0001
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