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A-443654

Synonyms

SourcesNames Used
GDSC1000A-443654
PharmacoGx A-443654

External IDs

DatabaseIdentifier
Smiles: CC1=C2C=C(C=CC2=NN1)C3=CC(=CN=C3)OCC(CC4=CNC5=CC=CC=C54)N
Inchikey: YWTBGJGMTBHQTM-IBGZPJMESA-N
Pubchem: 10172943

Cell lines tested with A-443654

426 cell lines have been tested with this compound, using data from 1 dataset(s).
HCC2218 breast GDSC10001
NCI-H2196 lung GDSC10001
Daudi haematopoietic and lymphoid tissue GDSC10001
SK-NEP-1 bone GDSC10001
L-1236 haematopoietic and lymphoid tissue GDSC10001
NCI-H226 lung GDSC10001
K5 thyroid GDSC10001
DOHH-2 haematopoietic and lymphoid tissue GDSC10001
KLE endometrium GDSC10001
SUP-HD1 haematopoietic and lymphoid tissue GDSC10001
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Top molecular features associated with response to A-443654


Feature TypeStandardized
Nominal ANOVA
mRNA HNRNPK GDSC1000 AAC 0.2 0.0002
mRNA ARF6 GDSC1000 AAC 0.21 0.0002
mRNA TMEM55A GDSC1000 AAC -0.21 0.0003
mRNA C1GALT1C1 GDSC1000 AAC 0.2 0.0003
mRNA ASIP GDSC1000 AAC -0.19 0.0003
mRNA PPP1R2 GDSC1000 AAC 0.19 0.0004
mRNA ANO10 GDSC1000 AAC -0.19 0.0004
mRNA SPG21 GDSC1000 AAC -0.18 0.0004
mRNA HFE GDSC1000 AAC 0.21 0.0005
mRNA C1orf216 GDSC1000 AAC -0.18 0.0005
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