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A-443654

Synonyms

SourcesNames Used
GDSC1000A-443654
PharmacoGx A-443654

External IDs

DatabaseIdentifier
Smiles: CC1=C2C=C(C=CC2=NN1)C3=CC(=CN=C3)OCC(CC4=CNC5=CC=CC=C54)N
Inchikey: YWTBGJGMTBHQTM-IBGZPJMESA-N
Pubchem: 10172943

Cell lines tested with A-443654

426 cell lines have been tested with this compound, using data from 1 dataset(s).
HCC2218 breast GDSC10001
NCI-H2196 lung GDSC10001
Daudi haematopoietic and lymphoid tissue GDSC10001
SK-NEP-1 bone GDSC10001
L-1236 haematopoietic and lymphoid tissue GDSC10001
NCI-H226 lung GDSC10001
K5 thyroid GDSC10001
DOHH-2 haematopoietic and lymphoid tissue GDSC10001
KLE endometrium GDSC10001
SUP-HD1 haematopoietic and lymphoid tissue GDSC10001
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Top molecular features associated with response to A-443654


Feature TypeStandardized
Nominal ANOVA
mRNA ABCB1 GDSC1000 AAC -0.28 1e-06
mRNA PRRT4 GDSC1000 AAC -0.26 2e-05
mRNA SEC62 GDSC1000 AAC 0.21 2e-05
mRNA SLURP1 GDSC1000 AAC 0.22 3e-05
mRNA CD38 GDSC1000 AAC 0.28 4e-05
mRNA OLFML2A GDSC1000 AAC 0.27 4e-05
mRNA LY9 GDSC1000 AAC 0.23 5e-05
mRNA HAP1 GDSC1000 AAC -0.21 9e-05
mRNA TMEM229A GDSC1000 AAC -0.25 0.0001
mRNA TBKBP1 GDSC1000 AAC -0.21 0.0001
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