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FIMM

Acronym

Institute for Molecular Medicine Finland (FIMM)

Description

The Institute for Molecular Medicine Finland (FIMM) cell line sensitivity dataset consists of cancer cell lines screened with a small set of anti-cancer therapies profiled using a platform developed for an Individualized Systems Medicine approach for screening patient tumour. The study sought to establish the effects of concentration range, cell viability assay and sensitivity measures on consistency in drug response profiling and argue for the standardization of protocols across laboratories to improve the utility of in vitro screening for personalized medicine approaches.

Publications

Mpindi, J. P. et al. Consistency in drug response profiling. Nature 540, E5–E6 (2016).

Pemovska, T. et al. Individualized Systems Medicine Strategy to Tailor Treatments for Patients with Chemorefractory Acute Myeloid Leukemia. Cancer Discov 3, 1416–1429 (2013).

Data type

Data Type Assay/Platform Raw Processed
Pharmacological CellTiter Glo Yes DSS

PharmacoGx

PharmacoSet object for: FIMM

All cell lines tested in FIMM

50 cell lines have been tested in this dataset.
RMG-IRPMI-8226
SIG-M5SK-BR-3
SK-OV-3SKM-1
SRT47D
THP-1ZR-75-1
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